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Antigenic Specificity | Human TP53 / p53 |
Clone | [BP53-12] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a,k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Recombinant human p53 protein. Hybridoma: Produced by the fusion between BALB/c mouse splenocytes and mouse myeloma P3-X63/AG8.653 cells using conventional hybridoma technology. Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. |
Immunogen | Immunogen Description: Recombinant human TP53 / p53. |
Other Names | [TP53 / p53 (clone BP53-12) IHC-plus; TP53; BCC7; Cellular tumor antigen p53; p53; TRP53; p53 tumor suppressor; Phosphoprotein p53; Antigen NY-CO-13; Tumor protein p53; Tumor suppressor p53; LFS1; Human TP53; p53], [p53] |
Gene, Accession # | [TP53], Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637 |
Catalog # | MBS245002 |
Price | $595 |
Order / More Info | Human TP53 / p53 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |