Phospho-LAT (Y191) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-LAT (Y191)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
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DescriptionSpecificity: Phospho-LAT (Y191) Antibody detects endogenous levels of total Phospho-LAT (Y191). Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
ImmunogenImmunogen: A synthesized peptide derived from human Phospho-LAT (Y191)
Other Names[36 kDa phospho-tyrosine adaptor protein; LAT1; lat; pp36], [LAT; LAT; LAT1; pp36; IMD52; pp36]
Gene, Accession #[LAT], Gene ID: 27040, NCBI: NP_001014987.1, UniProt: O43561
Catalog #MBS477773
Price$335
Order / More InfoPhospho-LAT (Y191) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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