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Antigenic Specificity | GRIN2B (Phospho-Ser1303) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of GRIN2B only when phosphorylated at serine 1303. N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.Adams S.L., Biochim. Biophys. Acta 1260:105-108(19 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 1303(Q-H-S(p)-Y-D) derived from Human GRIN2B. |
Other Names | [GRIN2B; NMDE2; NME2; NR2B; NR3] |
Gene, Accession # | [GRIN2B], Gene ID: 2904, NCBI: NP_000825.2, UniProt: Q13224 |
Catalog # | MBS9412497 |
Price | $200, $255 |
Order / More Info | GRIN2B (Phospho-Ser1303) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |