Edit |   |
---|---|
Antigenic Specificity | Grik1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the carboxy terminus of the human Grik1. |
Other Names | [Glutamate receptor ionotropic kainate 1, glutamate receptor 5, gluR5, excitatory amino acid receptor 3, eea3] |
Gene, Accession # | [Grik1], Gene ID: 2897, NCBI: NP_000821.1, UniProt: P39086 |
Catalog # | MBS9404661 |
Price | $320 |
Order / More Info | Grik1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |