S100A16 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityS100A16
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: S100A16 antibody detects endogenous levels of total S100A16. Function: Calcium-binding protein. Binds one calcium ion per monomer (PubMed:17030513). Can promote differentiation of adipocytes (in vitro) (By similarity). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake (By similarity).Subunit Structure: Homodimer (PubMed:17030513, PubMed:21046186). Interacts with TP53 (By similarity).Similarity: S100A16 proteins, but not other S100 proteins, have only one functional Ca2+ binding site per monomer. Upon Ca2+ binding, undergoes conformational changes leading to the exposure of hydrophobic patches which could be implicated in the Ca2+-dependent
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Nucleus > Nucleolus. Cytoplasm. Primarily nucleolar. Translocates from the nucleolus to the cytoplasm in response to an increase of intracellular calcium levels. Tissue Specificity: Ubiquitous (PubMed:14684152). Highly expressed in esophagus, adipose tissues and colon. Expressed at lower level in lung, brain, pancreas and skeletal muscle. Expression is up-regulated in tumors of bladder, lung, thyroid gland, pancreas and ovary (PubMed:1468415
Other Names[2300002L21Rik; AAG13; Aging associated gene 13 protein; Aging associated protein 13; Aging-associated gene 13 protein; AI325039; AI663996; DT1P1A7; MGC17528; Protein S100 A16; Protein S100-A16; Protein S100-F; Protein S100F; S100 calcium binding protein A16; S100 calcium-binding protein A16; S100A16; S100F; S10AG_HUMAN]
Gene, Accession #[S100A16], Gene ID: 140576, NCBI: NP_001303936.1, UniProt: Q96FQ6
Catalog #MBS9605807
Price$240, $280
Order / More InfoS100A16 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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