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Antigenic Specificity | S100A16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: S100A16 antibody detects endogenous levels of total S100A16. Function: Calcium-binding protein. Binds one calcium ion per monomer (PubMed:17030513). Can promote differentiation of adipocytes (in vitro) (By similarity). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake (By similarity).Subunit Structure: Homodimer (PubMed:17030513, PubMed:21046186). Interacts with TP53 (By similarity).Similarity: S100A16 proteins, but not other S100 proteins, have only one functional Ca2+ binding site per monomer. Upon Ca2+ binding, undergoes conformational changes leading to the exposure of hydrophobic patches which could be implicated in the Ca2+-dependent |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nucleus > Nucleolus. Cytoplasm. Primarily nucleolar. Translocates from the nucleolus to the cytoplasm in response to an increase of intracellular calcium levels. Tissue Specificity: Ubiquitous (PubMed:14684152). Highly expressed in esophagus, adipose tissues and colon. Expressed at lower level in lung, brain, pancreas and skeletal muscle. Expression is up-regulated in tumors of bladder, lung, thyroid gland, pancreas and ovary (PubMed:1468415 |
Other Names | [2300002L21Rik; AAG13; Aging associated gene 13 protein; Aging associated protein 13; Aging-associated gene 13 protein; AI325039; AI663996; DT1P1A7; MGC17528; Protein S100 A16; Protein S100-A16; Protein S100-F; Protein S100F; S100 calcium binding protein A16; S100 calcium-binding protein A16; S100A16; S100F; S10AG_HUMAN] |
Gene, Accession # | [S100A16], Gene ID: 140576, NCBI: NP_001303936.1, UniProt: Q96FQ6 |
Catalog # | MBS9605807 |
Price | $240, $280 |
Order / More Info | S100A16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |