HNRNPK Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-HNRNPK antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | HNRNPK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Heterogeneous nuclear ribonucleoprotein K (hnRNP K) belongs to a family of RNA binding multiprotein complexes (hnRNP proteins) that facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm (1-3). hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences (4, 5). Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis (6), transcriptional regulation (7), and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor (8, 9). hnRNP K coordinates with p53 to regulate its target gene transcription in response to DNA damage. Pr |
| Immunogen | Immunogen: Recombinant protein of human HNRNPK Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CSBP; FLJ41122; HNRPK; TUNP] |
| Gene, Accession # | [HNRNPK], Gene ID: 3190, NCBI: NP_001305115.1, UniProt: P61978 |
| Catalog # | MBS8502468 |
| Price | $310 |
| Order / More Info | HNRNPK Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Dreyfuss, G. et al. (1993) Annu Rev Biochem 62, 289-321. 2. Siomi, H. et al. (1994) Cell 77, 33-9. 3. Miau, L.H. et al. (1998) J Biol Chem 273, 10784-91. 4. Tomonaga, T. and Levens, D. (1995) J Biol Chem 270, 4875-81. 5. Choi, H.S. et al. (2009) Biochem Biophys Res Commun 380, 431-6. 6. Bustelo, X.R. et al. (1995) Mol Cell Biol 15, 1324-32. 7. Michelotti, E.F. et al. (1996) Mol Cell Biol 16, 2350-60. 8. Zhou, R. et al. (2010) Int J Cancer 126, 395-404. 9. Matta, A. et al. (2009) Int J Cancer 125, 1398-406. 10. Moumen, A. et al. (2005) Cell 123, 1065-78. 11. Ostareck-Lederer, A. et al. (2002) Mol Cell Biol 22, 4535-43. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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