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Antigenic Specificity | IFI16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds double-stranded DNA. Binds preferentially to supercoiled DNA and cruciform DNA structures. Seems to be involved in transcriptional regulation. May function as a transcriptional repressor. Could have a role in the regulation of hematopoietic differentiation through activation of unknown target genes. Controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein. May be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA binding and modulating TP53 phosphorylation status. Seems to be involved in energy-level-dependent activation of the ATM/ AMPK/TP53 pathway coupled to regulation of autophagy. May be involved in regu |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IFI16 (NP 005522.2). |
Other Names | [PYHIN2; IFNGIP1] |
Gene, Accession # | [IFI16], Gene ID: 3428, NCBI: NP_001193496.1, UniProt: Q16666 |
Catalog # | MBS8549296 |
Price | $280 |
Order / More Info | IFI16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |