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Antigenic Specificity | MAP3K5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens. Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS). Once activated, |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1300 to the C-terminus of human MAP3K5 (NP 005914.1). |
Other Names | [ASK1; MEKK5; MAPKKK5] |
Gene, Accession # | [MAP3K5], Gene ID: 4217, NCBI: NP_005914.1, UniProt: Q99683 |
Catalog # | MBS8548678 |
Price | $280 |
Order / More Info | MAP3K5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |