Cyclin B1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Cyclin B1 |
| Clone | [V92.1] |
| Host Species | Mouse |
| Reactive Species | human, mouse, hamster. |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: It recognizes a protein of 55-62kDa, identified as cyclin B1. In mammals, cyclin B associates with inactive p34cdc2, which facilitates phosphorylation of p34cdc2 at aa 14Thr and 15Tyr. This maintains the inactive state until the end of G2-phase. The inactive cyclin B-p34cdc2 complex continues to accumulate in the cytoplasm until the completion of DNA synthesis, when Cdc25, a specific protein phosphatase, dephosphorylates aa 14Thr and 15Tyr of p34cdc2 rendering the complex active at the G2/M boundary. This mitotic kinase complex remains active until the metaphase/anaphase transition when cyclin B is degraded. This degradation process is ubiquitin-dependent and is necessary for the cell to exit mitosis. So, cyclin B-p34cdc2 plays |
| Immunogen | Immunogen: Hamster Cyclin B1 protein Quantity and Buffer: 0.5 ml at 200ug/ml with BSA and azide |
| Other Names | [CCNB; CCNB1; CCNB1_HUMAN; G2 Mitotic Specific Cyclin B1], [CCNB1; CCNB1; CCNB; CCNB] |
| Gene, Accession # | [CCNB1], Gene ID: 891, NCBI: NP_114172.1, UniProt: P14635 |
| Catalog # | MBS438370 |
| Price | $190, $340, $340 |
| Order / More Info | Cyclin B1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Garner AP et al. Oncogene 21:8089-104 (2002)2. Minemoto Y et al. Exp Cell Res 262:37-48 (2001) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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