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Antigenic Specificity | UBC9 (UBE2I) (N-term), 1-30 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: zebrafish, chicken, mouse, rat, Xenopus) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This UBC9 (UBE2I) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBC9 (UBE2I). UBE2I (Ubc9) is a member of the E2 family and is specific for the conjugation of SUMO to a variety of target proteins. SUMO conjugation to target proteins is mediated by a different, but analogous, pathway to ubiquitinylation. This E2 is unusual in that it interacts directly with protein substrates that are modified by sumoylation, and may play a role in substrate recognition. UBE2I can mediate the conjugation of SUMO-1 to a variety of proteins including RanGAP1, I?B?, and PML without the requirement of an E3 ligase. UBE2I is essential for nuclear architecture and c |
Immunogen | n/a |
Other Names | [SUMO-conjugating enzyme UBC9; 632-; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; p18; UBE2I; UBC9; UBCE9] |
Gene, Accession # | [UBE2I], Gene ID: 7329, NCBI: NP_003336.1, UniProt: P63279 |
Catalog # | MBS9202059 |
Price | $165, $370 |
Order / More Info | UBC9 (UBE2I) (N-term), 1-30 Antibody from MYBIOSOURCE INC. |
Product Specific References | Biochem Biophys Res Commun. 2002 Aug 30;296(4):870-6. Genomics. 1996 Oct 15;37(2):183-6. Cytogenet Cell Genet. 1996;75(4):222-3. Cytogenet Cell Genet. 1996;72(1):86-9. |