AGT - C-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAGT - C-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bo
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AGT
Other Names[angiotensinogen preproprotein; Angiotensinogen; angiotensinogen; angiotensinogen; Serpin A8Cleaved into the following 8 chains:Angiotensin-1; Alternative name(s):; Angiotensin 1-10; Angiotensin I; Ang IAngiotensin-2; Alternative name(s):; Angiotensin 1-8; Angiotensin II; Ang IIAngiotensin-3; Alternative name(s):; Angiotensin 2-8; Angiotensin III; Ang III; Des-Asp[1]-angiotensin IIAngiotensin-4; Alternative name(s):; Angiotensin 3-8; Angiotensin IV]
Gene, Accession #[AGT], Gene ID: 183, NCBI: NP_000020.1, UniProt: P01019
Catalog #MBS3223124
Price$335
Order / More InfoAGT - C-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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