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Antigenic Specificity | APOB48R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: APOB48R antibody detects endogenous levels of total APOB48R. Function: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.Subunit Structure: Homodimer.Post-translational Modifications: There are 2 forms in m |
Immunogen | Immunogen: A synthesized peptide derived from human APOB48R Subcellular Location: Cell Membrane. Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein. Tissue Specificity: Expressed in peripheral blood leukocytes > bone marrow = spleen > lymph node, and only faintly visible in appendix and thymus. Expressed in the brain, heart, kidney, liver, lung, pancreas, and placenta. Expressed primarily by reticuloendothelial cell |
Other Names | [apo b-100; APOB; apoB-48R; APOBR; APOBR_HUMAN; Apolipoprotein B receptor; Apolipoprotein B-100 receptor; Apolipoprotein B-48 receptor; Apolipoprotein B48 receptor] |
Gene, Accession # | [APOB48R], Gene ID: 55911, NCBI: NP_061160.3, UniProt: Q0VD83 |
Catalog # | MBS9603006 |
Price | $240, $280 |
Order / More Info | APOB48R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |