DMRT1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | DMRT1 |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Doublesex- and mab-3-related transcription factor 1(DMRT1) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene. This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur wh |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human DMRT1 (98-128aa RDCQCKKCNLIAERQRVMAAQVALRRQQAQE), different from the related mouse sequence by one amino acid. Ig Type: Rabbit IgG |
| Other Names | [Doublesex- and mab-3-related transcription factor 1; CT154; DM domain expressed in testis 1; DM domain expressed in testis protein 1; DM domain gene expressed in testis; DMRT 1; dmrt1; DMRT1_HUMAN; DMT 1; DMT1; Doublesex and mab 3 related transcription factor 1; Doublesex- and mab-3-related transcription factor 1; doublesex and mab-3 related transcription factor 1], [DMRT1; DMRT1; DMT1; CT154; DMT1] |
| Gene, Accession # | [DMRT1], Gene ID: 1761, NCBI: NP_068770.2, UniProt: Q9Y5R6 |
| Catalog # | MBS178161 |
| Price | $315 |
| Order / More Info | DMRT1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Entrez Gene: DMRT1 doublesex and mab-3 related transcription factor 1. 2. Raymond CS, Shamu CE, Shen MM, Seifert KJ, Hirsch B, Hodgkin J, Zarkower D (February 1998). Evidence for evolutionary conservation of sex-determining genes.Nature 391 (6668): 691-5. 3. Smith CA, Roeszler KN, Ohnesorg T, Cummins DM, Farlie PG, Doran TJ, Sinclair AH (August 2009). The avian Z-linked gene DMRT1 is required for male sex determination in the chicken. Nature 461(7261): 267-71. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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