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Antigenic Specificity | Human STAT6 |
Clone | [STAAD23A] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 100 ug/ml (1.0 ml) |
Applications | ELISA (EIA), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [NCBI Entrez Gene Summary] |
Immunogen | n/a |
Other Names | [signal transducer and activator of transcription 6, interleukin-4 induced (STAT6); STAT6B; STAT6C; D12S1644; IL-4-STAT], [STAT6; STAT6; STAT6B; STAT6C; D12S1644; IL-4-STAT] |
Gene, Accession # | [STAT6], Gene ID: 6778, NCBI: NP_003144.3 |
Catalog # | MBS120038 |
Price | $395 |
Order / More Info | Human STAT6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |