Hrk Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Hrk |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Hrk Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Hrk, a pro-apoptotic member of the Bcl-2 homology domain-3 (BH3)-only group of the Bcl-2 family of proteins, was also identified as novel protein induced during programmed neuronal death. It lacks significant homology to other Bcl-2 family members except for an 8-amino acid region that is similar to the BH3 motif of Bik. Hrk regulates apoptosis through interaction with the anti-apoptotic proteins Bcl-2 and Bcl-XL via this domain. It does not interact with the pro-apoptotic proteins Bax, Bak, or Bcl-XS. Hrk localizes to mitochondrial membranes in a pattern similar to that previously reported for Bcl-2 and Bcl-XL. |
| Immunogen | Immunogen: HRK antibody was raised against a 15 amino acid synthetic peptide from near the center of human Hrk. Buffer: Hrk Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [Hrk; DP5; HARAKIRI; BID3; Activator of apoptosis harakiri; BH3-interacting domain-containing protein 3; harakiri, BCL2 interacting protein (contains only BH3 domain)], [HRK; HRK; DP5; HARAKIRI; BID3] |
| Gene, Accession # | [HRK], Gene ID: 8739, NCBI: NP_003797, UniProt: O00198 |
| Catalog # | MBS151175 |
| Price | $375 |
| Order / More Info | Hrk Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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