HSP70/HSC70 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HSP70/HSC70 |
| Clone | [N27F3-4] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat, bovine, C. elegans, beluga, dog, chicken, Fruit Fly, fish, guinea pig, hamster, monkey, porcine, plant, rabbit, sheep, Xenopus |
| Isotype | IgG1 |
| Format | APC-Cy7 conjugate |
| Size | 0.2 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS), Immuno-Electron Microscopy (IEM) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~72 (HSP) and ~73 kDa (HSC). HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 50% identity (2). The N-terminal two thirds of HSP70s are more conserved than the C-terminal third. HSP70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides (3). When HSC70 (constitutively expressed) present in mammalian cells was truncated, ATP bindin |
| Immunogen | Immunogen: Recombinant HSP70/HSC70 |
| Other Names | [Mouse Human HSP70/HSC70 IgG1; HSP70/HSC70 : APC/Cy7; HSP70 1; HSP70 2; HSP70.1; HSP72; HSPA1; HSPA1A; HSPA1B] |
| Gene, Accession # | [HSP70/HSC70], Gene ID: 3303, NCBI: NP_005336.3, UniProt: P0DMV8 |
| Catalog # | MBS8002116 |
| Price | $660 |
| Order / More Info | HSP70/HSC70 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Welch W.J. and Suhan J.P. (1986) J.Cell Biol. 103: 2035-2050. 2. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993), J. Mol. Evol.38 (1): 1-17. 3. Rothman J. (1989) Cell 59: 591-601. 4. DeLuca-Flaherty et al. (1990), Cell 62: 875-887. 5. Bork P., Sander C. & Valencia A. (1992) Proc. Nut1 Acad. Sci. USA 89: 7290-7294. 6. Fink A.L. (1999) Physiol. Rev. 79: 425-449. 7. Polanonka-Grabowska R. et. al. (1997) Blood 90: 1516-1526. 8. Schnell D.J. et. al. (1994) Science 266: 1007-1012. 9. Kabakov A.E., et. al. (2002) Am. J.Physiol. 283(2): C521-C534. 10. Ricart J. et. al. (1997) Biochem. J. 324: 635-643. 11. Hang H. and Fox M.H. (1995) Cytometry 19(2): 119-125. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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