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Antigenic Specificity | MEK 1/2 (pSer217/pSer221) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti MEK 1/2 (pSer217/pSer221) antibody recognizes MAPK/ERK kinase 1 (MEK 1) and MAPK/ERK kinase 2 (MEK 2), also known as MAP kinase kinase 1 (MAPKK 1) and MAP kinase kinase 2 (MAPKK 2) respectively, when phosphorylated at serine 217 and serine 221. MEK 1 and MEK 2 are integral components of the MAP kinase cascade that regulate cell growth and differentiation. MEK1 and MEK2 are phosphorylated at serine 217 and serine 221 by Raf kinases, increasing the activity or MEK 1 and MEK 2 (Matallanas et al. 2011). |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 217/221 of human MEK 1/2 |
Other Names | [MEK 1/2 (pSer217/pSer221)], [MAP2K2; MAP2K2; CFC4; MEK2; MKK2; MAPKK2; PRKMK2; MEK2; MKK2; PRKMK2; MAP kinase kinase 2; MAPKK 2; MEK 2] |
Gene, Accession # | [MAP2K2], Gene ID: 5605, NCBI: P36507.1, UniProt: P36507 |
Catalog # | MBS225287 |
Price | $375 |
Order / More Info | MEK 1/2 (pSer217/pSer221) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |