HPV-18 (Human Papilloma Virus 18) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHPV-18 (Human Papilloma Virus 18)
Clone[HPV18/1297]
Host SpeciesMouse
Reactive SpeciesType 18 of human Papilloma Virus (HPV-18)
IsotypeIgG1, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis has shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detec
ImmunogenImmunogen: HPV18 E6-β-galactosidase fusion protein
Other Names[E6; Human Papilloma Virus; HPV type 18 E6; Protein E6]
Gene, Accession #[HPV-18]
Catalog #MBS4381462
Price$190, $340, $340
Order / More InfoHPV-18 (Human Papilloma Virus 18) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesReich, N.C., et al. 1983. Mol. Cell. Biol. 3: 2143-2150.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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