Caspase-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, monkey
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: Caspase-3 Polyclonal Antibody detects endogenous levels of Caspase-3 protein. CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 3 cleaves and activates caspases 6, 7 and 9, and caspase 3 itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alter
ImmunogenImmunogen: Synthesized peptide derived from the N-terminal region of human Caspase-3 at AA range: 20-100
Other Names[Rabbit Caspase-3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1]
Gene, Accession #[CASP3], Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574
Catalog #MBS9700795
Price$130, $220, $325
Order / More InfoCaspase-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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