Human Apoptosis-Inducing Factor, Mitochondrion-Associated 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Apoptosis-Inducing Factor, Mitochondrion-Associated 1
Clone[PAT22E9AT]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a k
FormatProtein A purified
Size0.005 mg, 0.02 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionApoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) is a mitochondrial protein which translocates to the nucleus once apoptosis has been initiated. AIFM1 causes DNA fragmentation and chromatin condensation and also triggers the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression prevents the release of AIFM1 from mitochondria, but doesn't block its apoptogenic activity.
ImmunogenImmunogen: Anti-human AIFM1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human AIFM1 protein 98-609 amino acids purified from E Coli.
Other Names[AIFM1; Apoptosis-inducing factor 1; mitochondrial; Programmed cell death protein 8; AIFM1; AIF; PDCD8; CMTX4; COWCK; COXPD6; isoform 2 precursor; Apoptosis-Inducing Factor; Mitochondrion-Associated; 1; Apoptosis-Inducing Factor Mitochondrion-Associated 1, Mouse Human], [AIFM1; AIFM1; AIF; CMT2D; CMTX4; COWCK; DFNX5; NADMR; NAMSD; PDCD8; COXPD6; AIF; PDCD8]
Gene, Accession #[AIFM1], Gene ID: 9131, NCBI: NP_004199.1, UniProt: O95831
Catalog #MBS146669
Price$140, $205, $505
Order / More InfoHuman Apoptosis-Inducing Factor, Mitochondrion-Associated 1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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