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Antigenic Specificity | Human Apoptosis-Inducing Factor, Mitochondrion-Associated 1 |
Clone | [PAT22E9AT] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a k |
Format | Protein A purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) is a mitochondrial protein which translocates to the nucleus once apoptosis has been initiated. AIFM1 causes DNA fragmentation and chromatin condensation and also triggers the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression prevents the release of AIFM1 from mitochondria, but doesn't block its apoptogenic activity. |
Immunogen | Immunogen: Anti-human AIFM1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human AIFM1 protein 98-609 amino acids purified from E Coli. |
Other Names | [AIFM1; Apoptosis-inducing factor 1; mitochondrial; Programmed cell death protein 8; AIFM1; AIF; PDCD8; CMTX4; COWCK; COXPD6; isoform 2 precursor; Apoptosis-Inducing Factor; Mitochondrion-Associated; 1; Apoptosis-Inducing Factor Mitochondrion-Associated 1, Mouse Human], [AIFM1; AIFM1; AIF; CMT2D; CMTX4; COWCK; DFNX5; NADMR; NAMSD; PDCD8; COXPD6; AIF; PDCD8] |
Gene, Accession # | [AIFM1], Gene ID: 9131, NCBI: NP_004199.1, UniProt: O95831 |
Catalog # | MBS146669 |
Price | $140, $205, $505 |
Order / More Info | Human Apoptosis-Inducing Factor, Mitochondrion-Associated 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |