Nucleolin (Marker of Human Cells) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Nucleolin (Marker of Human Cells) |
| Clone | [NCL/902] |
| Host Species | Mouse |
| Reactive Species | humandoes not react with mouse, rat or cow. |
| Isotype | IgG1, kappa |
| Format | CF488 conjugate |
| Size | 0.5 mL |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of ~76kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be |
| Immunogen | Immunogen: Recombinant human NCL protein |
| Other Names | [NCL; Nucl; Nucleolin; Protein C23] |
| Gene, Accession # | [NCL], Gene ID: 4691, NCBI: NP_005372.2, UniProt: P19338 |
| Catalog # | MBS4381112 |
| Price | $340 |
| Order / More Info | Nucleolin (Marker of Human Cells) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Qiu W, Zhou F, Zhang Q, Sun X, Shi X, Liang Y, Wang X, Yue L. Overexpression of nucleolin and different expression sites both related to the prognosis of gastric cancer. APMIS. 2013;121(10):919-25. 2. Fujiki H, Watanabe T, Suganuma M. Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands. J Cancer Res Clin Oncol. 2014;140(5):689-99. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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