Atg4C Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAtg4C
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesn/a
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration1mg/ml
ApplicationsImmunoblotting (IB)
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DescriptionThis antibody recognizes human and rat Atg4C. Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. Recent studies demonstrated that Atg4D is a substrate for caspase-3 during apoptosis. Truncated Atg4D has increased priming and delipidation effects on the Atg8 paralogue GABARAP-L1 in vitro and induces cell death when overexpressed in human cells. In addition, Atg4D-mediated apoptosis is facilitated by a putative C-terminal BH3 domain and is preceded by recruitment of Atg4D to mitochondria, suggesting that Atg4D plays an important role at the interface between autophagy and apoptosis.
ImmunogenAntigen: Synthetic peptide corresponding to amino acids at the N-terminus of human Atg4C.
Other Names[cysteine protease ATG4C; Cysteine protease ATG4C; cysteine protease ATG4C; autophagy related 4C cysteine peptidase; AUT-like 3 cysteine endopeptidase; Autophagin-3; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C], [ATG4C; ATG4C; APG4C; AUTL1; AUTL3; APG4-C; APG4C; AUTL1; AUTL3]
Gene, Accession #[Atg4C], Gene ID: 84938, NCBI: NP_116241.2, UniProt: Q96DT6
Catalog #MBS191002
Price$410
Order / More InfoAtg4C Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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