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Antigenic Specificity | Atg4C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Immunoblotting (IB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human and rat Atg4C. Autophagy is a catabolic process that results in the degradation of bulk cytoplasmic contents within autophagosomes and lysosomes. Recent studies demonstrated that Atg4D is a substrate for caspase-3 during apoptosis. Truncated Atg4D has increased priming and delipidation effects on the Atg8 paralogue GABARAP-L1 in vitro and induces cell death when overexpressed in human cells. In addition, Atg4D-mediated apoptosis is facilitated by a putative C-terminal BH3 domain and is preceded by recruitment of Atg4D to mitochondria, suggesting that Atg4D plays an important role at the interface between autophagy and apoptosis. |
Immunogen | Antigen: Synthetic peptide corresponding to amino acids at the N-terminus of human Atg4C. |
Other Names | [cysteine protease ATG4C; Cysteine protease ATG4C; cysteine protease ATG4C; autophagy related 4C cysteine peptidase; AUT-like 3 cysteine endopeptidase; Autophagin-3; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C], [ATG4C; ATG4C; APG4C; AUTL1; AUTL3; APG4-C; APG4C; AUTL1; AUTL3] |
Gene, Accession # | [Atg4C], Gene ID: 84938, NCBI: NP_116241.2, UniProt: Q96DT6 |
Catalog # | MBS191002 |
Price | $410 |
Order / More Info | Atg4C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |