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Antigenic Specificity | CSK |
Clone | [2B4-C6-A10] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of CSK and does not cross-react with related proteins. Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface rece |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Purified recombinant human CSK protein fragments expressed in E Coli. |
Other Names | [C SRC; C SRC kinase; C src Tyrosine Kinase; C-SRC kinase; c-src tyrosine kinase; Csk A; CSK; CSK_HUMAN; CYTOPLASMIC TYROSINE KINASE; EC2.7.10.2; MGC112926; MGC117393; MGC154049; P60 Src; Protein tyrosine kinase CYL; Protein-tyrosine kinase CYL] |
Gene, Accession # | [CSK], Gene ID: 1445, NCBI: NP_001120662.1, UniProt: P41240 |
Catalog # | MBS9400026 |
Price | $200, $255 |
Order / More Info | CSK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |