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Antigenic Specificity | MCFD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LMAN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular g |
Immunogen | Immunogen: Recombinant protein of human MCFD2 (NP 644808.1). |
Other Names | [multiple coagulation factor deficiency protein 2 isoform A; Multiple coagulation factor deficiency protein 2; multiple coagulation factor deficiency protein 2; multiple coagulation factor deficiency 2; Neural stem cell-derived neuronal survival protein] |
Gene, Accession # | [MCFD2], Gene ID: 90411, NCBI: NP_001164977.1, UniProt: Q8NI22 |
Catalog # | MBS8566457 |
Price | $280 |
Order / More Info | MCFD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |