Human CD253: Low Endotoxin Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD253: Low Endotoxin |
| Clone | [2E5] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.5 mg |
| Concentration | IgG concentration 1.0 mg/ml |
| Applications | Flow cytometry (FC/FACS), Functional Assays (FN), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human CD253 antibody, clone 2E5 recognizes the 281 amino acid protein termed TNF related apoptosis-inducing ligand (TRAIL), also known as Apo2L. TRAIL is a cytotoxic protein closely related to Fas (CD95), which induces extensive apoptosis in a range of cell types. TRAIL induces apoptosis via the receptors DR4 and DR5. Most normal tissues are resistant to TRAIL induced apoptosis due to their expression of decoy receptors, DcR1 and DcR2, which antagonise TRAIL activity. TRAIL is expressed by cell lines, activated lymphocytes and on syncytiotrophoblast cells in first trimester pregnancy. This antibody neutralizes TRAIL activity. |
| Immunogen | Immunogen: Recombinant human CD253 (TRAIL) aa 95-281. Buffer Solution: Phosphate buffered saline Target Species: Human |
| Other Names | [tumor necrosis factor ligand superfamily member 10 isoform 2; Tumor necrosis factor ligand superfamily member 10; tumor necrosis factor ligand superfamily member 10; Apo-2 ligand; TNF-related apoptosis inducing ligand TRAIL; chemokine tumor necrosis factor ligand superfamily member 10; tumor necrosis factor (ligand) family, member 10; tumor necrosis factor apoptosis-inducing ligand splice variant delta; tumor necrosis factor (ligand) superfamily, member 10; Apo-2 ligand; Apo-2L; TNF-related apoptosis-inducing ligand; Protein TRAIL; CD_antigen: CD253], [TNFSF10; TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L; APO2L; TRAIL; Apo-2L; Protein TRAIL] |
| Gene, Accession # | [CD253], Gene ID: 8743, NCBI: NP_001177871.1, UniProt: P50591 |
| Catalog # | MBS219596 |
| Price | $675 |
| Order / More Info | Human CD253: Low Endotoxin Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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