p21 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | p21 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 100ug/100ul |
| Applications | Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli. This protein can interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair. This protein was reported to be specifically cleaved by CASP3-like caspases, which thus leads to a dramatic activation of CDK2, and |
| Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
| Other Names | [Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1) (CDKN1A), transcript variant 1, mRNA; Cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; CDK-interaction protein 1; DNA synthesis inhibitor; melanoma differentiation associated protein 6; wild-type p53-activated fragment 1; cyclin-dependent kinase inhibitor 1A (p21, Cip1); CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21], [CDKN1A; CDKN1A; P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1] |
| Gene, Accession # | [p21], Gene ID: 1026, NCBI: NP_000380.1 |
| Catalog # | MBS416389 |
| Price | $230 |
| Order / More Info | p21 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yao, CL et al. Thermal stress and cellular signaling processes in hemocytes of native (Mytilus californianus) and invasive (M. galloprovincialis) mussels: cell cycle regulation and DNA repair. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 165:159-68 (2013). PubMed: 23454628. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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