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Antigenic Specificity | BACE2 (CT) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-BACE2 (CT) [Rabbit antibody to peptide corresponding to aa 496-511 at the C-terminus of human BACE2.]. This antibody recognizes human BACE2 (approx. 75 kD). Accumulation of the amyloid- beta peptide (A beta ) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. A beta peptide is generated as a result of proteolytic cleavage of the beta -amyloid protein precursor (APP) at beta - and gamma -sites. beta -secretase was recently identified and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2). A BACE homolog was recently identified and designated BACE2, or Asp1, DRAP (for Down region aspartic protease), or memapsin 1. BACE2 cleaves APP at the beta - site and at a di |
Immunogen | Antigen: Peptide corresponding to aa 496- 511 of human BACE2. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194031 |
Price | $415 |
Order / More Info | BACE2 (CT) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |