CUL5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCUL5
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThe antibody detects endogenous levels of CUL5 protein. Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS (SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
ImmunogenImmunogen: Synthesized peptide derived from part region of human CUL5 protein at amino acid sequence of 560-640
Other Names[Rabbit CUL5; Cullin-5; CUL-5; Vasopressin-activated calcium-mobilizing receptor 1; VACM-1]
Gene, Accession #[CUL5], Gene ID: 8065, NCBI: NP_003469.2, UniProt: Q93034
Catalog #MBS9708883
Price$130, $220, $325
Order / More InfoCUL5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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