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Antigenic Specificity | NLK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of HeLa cell line, using NLK antibody. The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both Thr-183 and Tyr-185 is required for full enzymatic activation. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine (5, 6). Nlk, or nemo-like kinase, is a murine homolog of the Drosophila nemo (nmo) gene. N |
Immunogen | Immunogen: Recombinant protein of human NLK |
Other Names | [NLK, partial; NLK; NLK] |
Gene, Accession # | [NLK], NCBI: JAO87015.1 |
Catalog # | MBS4150278 |
Price | $385 |
Order / More Info | NLK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |