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Antigenic Specificity | MYSM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 2.2 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MYSM1 protein. Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human Myb-like, SWIRM and MPN domains 1 |
Other Names | [2ADUB; 2A-DUB; RP4-592A1.1] |
Gene, Accession # | [MYSM1], Gene ID: 114803, NCBI: NP_001078956.1, UniProt: Q5VVJ2 |
Catalog # | MBS9402008 |
Price | $255 |
Order / More Info | MYSM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |