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Antigenic Specificity | NBR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NBR1 antibody detects endogenous levels of NBR1. Function: Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets.Subunit Structure: Homooligomer and heterooligomer. Interacts with TRIM55 (By similarity). Interacts with SQSTM1, titin/TTN, RNF29, USP8, SQSTM1, MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2. Binds to ubiquitin and ubiquitinated proteins.Similarity: The PB1 domain mediates interaction with SQSTM1. |
Immunogen | Immunogen: A synthesized peptide derived from human NBR1. Subcellular Location: Cytoplasm. Cytoplasmic Vesicle > Autophagosome. Lysosome. Cytoplasm > Myofibril > Sarcomere > M line. In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog |
Other Names | [1A1 3B; 1A13B; B box protein; Cell migration-inducing gene 19 protein; KIAA0049; M17S2; Membrane component chromosome 17 surface marker 2; Membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125); MIG 19; MIG19; Migration inducing protein 19; NBR 1; Nbr1; NBR1, autophagy cargo receptor; NBR1_HUMAN; Neighbor of BRCA1 gene 1; Neighbor of BRCA1 gene 1 protein; Next to BRCA1 gene 1 protein; Ovarian carcinoma antigen CA125; Protein 1A1-3B] |
Gene, Accession # | [NBR1], Gene ID: 4077, NCBI: NP_001278500.1, UniProt: Q14596 |
Catalog # | MBS9603277 |
Price | $240, $280 |
Order / More Info | NBR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |