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Antigenic Specificity | MLPH (C-term), 541-569 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MLPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human MLPH. This gene encodes a member of the exophilin subfamily ofRab effector proteins. The protein forms a ternary complex with thesmall Ras-related GTPase Rab27A in its GTP-bound form and the motorprotein myosin Va. A similar protein complex in mouse functions totether pigment-producing organelles called melanosomes to the actincytoskeleton in melanocytes, and is required for visiblepigmentation in the hair and skin. A mutation in this gene resultsin Griscelli syndrome type 3, which is characterized by asilver-gray hair color and abnormal pigment distrib |
Immunogen | n/a |
Other Names | [Melanophilin; Exophilin-3; Slp homolog lacking C2 domains a; SlaC2-a; Synaptotagmin-like protein 2a; MLPH; SLAC2A] |
Gene, Accession # | [MLPH], Gene ID: 79083, NCBI: NP_001035932.1, UniProt: Q9BV36 |
Catalog # | MBS9210785 |
Price | $165, $370 |
Order / More Info | MLPH (C-term), 541-569 Antibody from MYBIOSOURCE INC. |
Product Specific References | Park, J.W., et al. J. Med. Genet. 43(7):598-608(2006) Seabra, M.C., et al. Traffic 5(6):393-399(2004) Fukuda, M., et al. J. Cell. Sci. 117 (PT 4), 583-591 (2004) : Lukusa, T., et al. Genet. Couns. 15(3):293-301(2004) Menasche, G., et al. J. Clin. Invest. 112(3):450-456(2003) |