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Antigenic Specificity | Mouse TRIAD3A (N-TERMINAL) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises an epitope within the N-terminal region (NT) of mouse TRIAD3A, a ubiquitously expressed E3 ubiquitin-protein ligase which plays an important role in the innate immune response. . . Regulation of the level and duration of Toll-like receptor (TLR) activation is vital in controlling a pro-inflammatory response, to prevent harm to the host. Several proteins involved in the regulation of TLR signaling have been described including ST2 and IL-1R-associated kinase M, along with many other adaptor proteins of the MyD88 family, which mediate TLR signal transduction. TRIAD3A, identified as a RING finger member of the E3 ligase family of proteins, binds to the cytoplasmic tail of several TLRs, notably TLR4 and TLR9, resulting in |
Immunogen | Immunogen: A 15 amino acid peptide located near mouse TRIAD3A amino-terminus. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to mouse TRIAD3A (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography. Target Species: Mouse |
Other Names | [E3 ubiquitin-protein ligase RNF216 isoform A; E3 ubiquitin-protein ligase RNF216; E3 ubiquitin-protein ligase RNF216; E3 ubiquitin ligase; triad domain-containing protein 3; ubcM4-interacting protein 83; ubiquitin-conjugating enzyme 7-interacting protein 1; ring finger protein 216; RING finger protein 216; Triad domain-containing protein 3; UbcM4-interacting protein 83; Ubiquitin-conjugating enzyme 7-interacting protein 1], [Rnf216; Rnf216; UIP83; C86502; TRIAD3; AI647468; AU019462; Ubce7ip1; 2810055G22Rik; F830018F18Rik; Triad3; Ubce7ip1; Uip83; Zin] |
Gene, Accession # | [TRIAD3A], Gene ID: 108086, NCBI: NP_542128.2, UniProt: P58283 |
Catalog # | MBS221309 |
Price | $375 |
Order / More Info | Mouse TRIAD3A (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |