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Antigenic Specificity | CCAR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CCAR1 antibody detects endogenous levels of total CCAR1. Function: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes inc |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm > Perinuclear Region. Tissue Specificity: Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors. Predicted Cross Reactivity: Bovine, Horse, Sheep, Dog Similarity: Bovine (100%), Horse (100%), Sheep (100%), Dog (100%) |
Other Names | [CARP-1; Carp1; Ccar1; CCAR1_HUMAN; Cell cycle and apoptosis regulatory protein 1; cell division cycle and apoptosis regulator 1; Cell division cycle and apoptosis regulator protein 1; Death inducer with SAP domain; FLJ10590; FLJ10839; FLJ13376; FLJ20734; MGC7730; RP11-437A18.1] |
Gene, Accession # | [CCAR1], Gene ID: 55749, NCBI: NP_001269888.1, UniProt: Q8IX12 |
Catalog # | MBS9603815 |
Price | $240, $280 |
Order / More Info | CCAR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |