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Antigenic Specificity | PARK7/Dj 1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteines, arginines and lysines residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of advanced glycation endproducts (AGE) (PubMed: 25416785). Plays an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease; functions probably related to its primary function (PubMed: 17015834, PubMed: 20304780, PubMed: 18711745, PubMed: 12796482, Pu |
Immunogen | Immunogen: A synthesized peptide derived from human PARK7. Subcellular Localization: Cell membrane; Lipid-anchor. Cytoplasm. Nucleus. Membrane raft. Mitochondrion. Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage (PubMed: 18711745). Detected in tau inclusio |
Other Names | [Protein deglycase DJ-1; DJ-1; 3.1.2.-; 3.5.1.-; Oncogene DJ1; Parkinson disease protein 7; PARK7], [PARK7] |
Gene, Accession # | [PARK7/Dj 1], Gene ID: 11315, NCBI: NP_001116849.1, UniProt: Q99497 |
Catalog # | MBS179440 |
Price | $160, $340, $340 |
Order / More Info | PARK7/Dj 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |