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Antigenic Specificity | ADAMTS13 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 13(ADAMTS13) detection. Background: ADAMTS13 (a disintegrin and metalloproteinase with athrombospondin type 1 motif, member 13), also known as VWFCP, is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. This gene is mapped to 9q34. |
Immunogen | Immunogen: E. coli-derived human ADAMTS13 recombinant protein (Position: A299-R488). Human ADAMTS13 shares 85.2% amino acid (aa) sequence identity with mouse ADAMTS13. |
Other Names | [ADAM TS; ADAM-TS 13; ADAM-TS13; ADAMTS 13; ADAMTS-13; ADAMTS13; C9orf8; TTP; vWF CP; vWF-CP; vWFCP; Q76LX8; A disintegrin and metalloproteinase with thrombospondin motifs 13; ADAM metallopeptidase with thrombospondin type 1 motif 13], [ADAMTS13; ADAMTS13; VWFCP; C9orf8; vWF-CP; ADAM-TS13; ADAMTS-13; C9orf8; ADAM-TS 13; ADAM-TS13; ADAMTS-13; vWF-CP; vWF-cleaving protease] |
Gene, Accession # | [ADAMTS13], Gene ID: 11093, NCBI: NP_620594.1, UniProt: Q76LX8 |
Catalog # | MBS178784 |
Price | $280 |
Order / More Info | ADAMTS13 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Fujimura Y, Matsumoto M, Yagi H, et al. (2002). Von Willebrand factor-cleaving protease and Upshaw-Schulman syndrome.. Int. J. Hematol. 75 (1): 25-34.2. Furlan M, Lammle B (2001). Aetiology and pathogenesis of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome: the role of von Willebrand factor-cleaving protease. Best Pract Res Clin Haematol 14 (2): 437-54. |