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Antigenic Specificity | PI3KCA (C-term), 1019-1050 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PI3KCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1019-1050 amino acids from the C-terminal region of human PI3KCA. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. This protein represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. PI3KCA has been found to be oncogenic and has been implicated in cervical cancers. |
Immunogen | n/a |
Other Names | [Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; PI3-kinase subunit alpha; PI3K-alpha; PI3Kalpha; PtdIns-3-kinase subunit alpha; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; PtdIns-3-kinase subunit p110-alpha; p110alpha; Phosphoinositide-3-kinase catalytic alpha polypeptide; Serine/threonine protein kinase PIK3CA; PIK3CA] |
Gene, Accession # | [PIK3CA], Gene ID: 5290, NCBI: NP_006209.2, UniProt: P42336 |
Catalog # | MBS9200737 |
Price | $165, $370 |
Order / More Info | PI3KCA (C-term), 1019-1050 Antibody from MYBIOSOURCE INC. |
Product Specific References | Tiwari, S. Nat Immunol. August; 10(8): 907?17 (2009). Ballou, L.M., et al., J. Biol. Chem. 278(26):23472-23479 (2003). Singh, B., et al., Genes Dev. 16(8):984-993 (2002). Shayesteh, L., et al., Nat. Genet. 21(1):99-102 (1999). Volinia, S., et al., Genomics 24(3):472-477 (1994). Hiles, I.D., et al., Cell 70(3):419-429 (1992). |