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Antigenic Specificity | RIG-I (Mouse) |
Clone | SS1A |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes mouse RIG-I. RIG-1/DDX58 (Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58) is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARD domains, a helicase ATP-binding domain and a helicase C-terminal domain. Predicted molecular weight approximately 107 kDa. RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses. RIG-1 and MDA5 (melanoma differentiation-associated gene 5) are key intracellular receptors that sense intracellular viral infection and trigger a signal for innate antiviral responses including the production of typeI IFN. Clone SS1A has been shown to be useful for Western blotting of the mouse RIG-1 protein. Involved in innate immune defense against viruses. RIG-1 ha |
Immunogen | Immunogen: Synthetic peptide corresponding to C-terminal mouse RIG-I conjugated to KLH. |
Other Names | [RIG-1; Retinoic acid-inducible gene 1 protein; DEAD-box protein 58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 M; Probable ATP-dependent RNA helicase DDX58], [Ddx58; Ddx58; RIG-I; RLR-1; C330021E21; 6430573D20Rik; RLR-1; RIG-1; RIG-I] |
Gene, Accession # | [RIG-I], Gene ID: 230073, NCBI: Q6Q899.2, UniProt: Q6Q899 |
Catalog # | MBS565029 |
Price | $310 |
Order / More Info | RIG-I (Mouse) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |