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Antigenic Specificity | DRD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:9003072, PubMed:16423344, PubMed:27659709, PubMed:29051383). Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase (PubMed:7512953, PubMed:7643093, PubMed:16423344, PubMed:27659709, PubMed:29051383). Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells. |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRD4 (NP 000788.2). |
Other Names | [D4DR] |
Gene, Accession # | [DRD4], Gene ID: 1815, NCBI: NP_000788.2, UniProt: P21917 |
Catalog # | MBS8544367 |
Price | $280 |
Order / More Info | DRD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |