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Antigenic Specificity | Human Cytochrome c |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. |
Immunogen | Immunogen: Recombinant Human Cytochrome c protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8385 / sc-7159 |
Other Names | [CYCS], [CYCS; CYCS; CYC; HCS; THC4; CYC] |
Gene, Accession # | [CYC], Gene ID: 54205, NCBI: NP_061820.1, UniProt: P99999 |
Catalog # | MBS1490104 |
Price | $160, $235 |
Order / More Info | Human Cytochrome c Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |