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Antigenic Specificity | Human IL-3 receptor alpha |
Clone | [11A23] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB), Neutralizing (N) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukin 3 (IL-3) is a pleiotropic cytokine that can stimulate proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. IL-3 exerts its activity through binding to a specific cell surface receptor known as IL-3 R. IL-3 R is a heterodimeric structure composed of a 70 kDa IL-3 R alpha subunit (CD123 or beta common) and a 120-140 kDa IL-3 R beta subunit (CD131). CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective hetero-receptor complex. |
Immunogen | Antigen: Recombinant Human IL-3 receptor alpha extracellular domain Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with purified human recombinant protein of IL-3R alpha extracellular domain. The IgG1 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
Other Names | [IL-3 R alpha, IL3ra], [IL3RA; IL3RA; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra; IL3R; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA] |
Gene, Accession # | [IL-3], Gene ID: 3563, NCBI: NP_001254642.1, UniProt: P26951 |
Catalog # | MBS692201 |
Price | $490 |
Order / More Info | Human IL-3 receptor alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |