NALP12 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNALP12
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionNALP12 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP12, also known as Monarch-1, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. NALP12 is thought to act as an attenuating factor of inflammation by suppressing inflammatory responses such as NF-κB activation by TLR-signaling molecules MyD88, IRAK-1, TRAF6 and RIPK1 in activated monocytes. Recent evidence suggests that mutations in NALP12 result in hereditary periodic fever syndromes.
ImmunogenImmunogen: NALP12 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human NALP12. Buffer: NALP12 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[NALP12; RNO; PAN6; RNO2; FCAS2; NALP12; PYPAF7; CLR19.3; RNO; NACHT; LRR and PYD domains-containing protein 12; Monarch-1; NLR family, pyrin domain containing 12], [NLRP12; NLRP12; RNO; PAN6; RNO2; FCAS2; NALP12; PYPAF7; CLR19.3; NALP12; PYPAF7; RNO]
Gene, Accession #[NLRP12], Gene ID: 91662, NCBI: NP_653288, UniProt: P59046
Catalog #MBS151244
Price$375
Order / More InfoNALP12 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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