Edit |   |
---|---|
Antigenic Specificity | DR5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DR5 is the DD containing receptor for TRAIL, Apo2, TRAIL-R2, TRICK2, or KILLER. DR5 transcript is widely expressed in normal tissues and in many types of tumor cells. Like DR3 and TNFR1, DR5 mediate apoptosis by FADD dependent pathway. Over-expression of DR5 induces apoptosis and activates NFkB. |
Immunogen | Immunogen: DR5 antibody was raised in Rabbit using synthetic peptide corresponding to residues surrounding amino acid 372 of mouse DR5 precursor as the immunogen. |
Other Names | [Rabbit DR5; DR5; DR5; CD262; DR 5; TRICK2A; DR-5; DR 5; TNFRSF10B; DR5; ZTNFR9; TRICK2; DR-5; TRICKB; TRAIL-R2; TRANCE-R; KILLER; Apo2] |
Gene, Accession # | [DR5], Gene ID: 8795 |
Catalog # | MBS5311152 |
Price | $430 |
Order / More Info | DR5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |