Edit |   |
---|---|
Antigenic Specificity | PKR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PKR Polyclonal Antibody detects endogenous levels of PKR protein. Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of eukaryotic translation initiation factor 2 alpha kinase 2 can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for EIF2AK2. |
Immunogen | Immunogen: Synthesized peptide derived from human PKR around the non-phosphorylation site of T446 |
Other Names | [Rabbit PKR; EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k] |
Gene, Accession # | [PKR], Gene ID: 5610, NCBI: NP_001129123.1, UniProt: P19525 |
Catalog # | MBS9702909 |
Price | $130, $220, $325 |
Order / More Info | PKR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |