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Antigenic Specificity | Factor VIIIc (Antihaemophilic Factor) |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 1 mg |
Concentration | n/a |
Applications | ELISA (EL/EIA), Neutralization |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human F.VIII as demonstrated by immunodiffusion and ELISA. No reactivity was observed with von Willebrand Factor. Factor VIII (antihemophilic globulin and Factor VIII:C) is a large glycoprotein (320kD) that circulates in plasma at ~200ng/ml. Synthesized in the liver, the majority of Factor VIII is cleaved during expression, resulting in a heterogeneous mixture of partially cleaved forms of F.VIII ranging in size from 200-280kD. The F.VIII is stabilized by association with von Willebrand Factor to form a F.VIII-vWF complex required for the normal survival of F.VIII in vivo (t1/2 of 8-12 hours). F.VIII is a pro-cofactor that is activated through limited proteolysis by thrombin. In this process F.VIIIa dissociates from vWF to combin |
Immunogen | Immunogen: Human Factor VIIIC (F.VIII) purified from concentrate |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS621342 |
Price | $360 |
Order / More Info | Factor VIIIc (Antihaemophilic Factor) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |