CLSTN1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CLSTN1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CLSTN1 antibody detects endogenous levels of total CLSTN1. Function: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by compet |
| Immunogen | Immunogen: A synthesized peptide derived from human CLSTN1 Subcellular Location: Endoplasmic Reticulum Membrane. Golgi Apparatus Membrane. Cell Projection. Cell Junction > Synapse > Postsynaptic Cell Membrane. Nucleus. Neurite Tips. Localized in the postsynaptic membrane of both excitatory and inhibitory synapses (By similarity). The AlcICD fragment is translocated to the nucleus upon interaction with APBB1. Tissue Specificity: Expressed in the brain and, a lower level, in the heart, skeletal mu |
| Other Names | [Alc alpha; Alc-alpha; Alcadein alpha 1; Alcadein alpha; Alcadein-alpha; alcalpha1; alcalpha2; Alzheimer related cadherin like protein; Alzheimer-related cadherin-like protein; C-terminal fragment 1-alpha; Cadherin related family member 12; Calsyntenin 1; Calsyntenin1; CDHR12; CLSTN 1; Clstn1; CS1; CSTN1; CSTN1_HUMAN; CTF1-alpha; FLJ32258; KIAA0911; Non classical cadherin XB31alpha; Non classical cadherin XB31alpha1; Non-classical cadherin XB31alpha; PIK3CD; SAlc-alpha; XB31alpha] |
| Gene, Accession # | [CLSTN1], Gene ID: 22883, NCBI: NP_001009566.1, UniProt: O94985 |
| Catalog # | MBS9608535 |
| Price | $240, $280 |
| Order / More Info | CLSTN1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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