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Antigenic Specificity | Human LINGO-1 |
Clone | [39R16] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Originally identified as a differentiation antigen of mesotheliomas, ovarian cystadenocarcinomas, and pancreatic adenocarcinomas, mesothelin is a glycosylphosphatidylinositol (GPI)-anchored, cell-surface glycoprotein predominantly secreted by cells of the mesothelium. Although mesothelin is expressed at restricted levels by normal mesothelial cells of the pleural, pericardial, and peritoneal membranes, aberrant expression has been documented in the aforementioned cancers, as well as in endometrioid uterine adenocarcinomas and squamous cell carcinomas of the esophagus, stomach, lung, and cervix. Proteolytic cleavage of mesothelin yields a soluble, polypeptide fragment-designated megakaryocyte-potentiating factor (MPF) based on its ability to |
Immunogen | n/a |
Other Names | [leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 isoform b; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat and Ig domain containing 1; Leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A], [LINGO1; LINGO1; LERN1; LRRN6A; UNQ201; LERN1; LRRN6A] |
Gene, Accession # | [LINGO-1], Gene ID: 84894, NCBI: NP_001288115.1, UniProt: Q96FE5 |
Catalog # | MBS692345 |
Price | $490 |
Order / More Info | Human LINGO-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |