TOLLIP (C-term), 221-250 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TOLLIP (C-term), 221-250 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This TOLLIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the C-terminal region of human TOLLIP. Toll like protein is a component of the signaling pathway of IL1 and Toll like receptors. It inhibits cell activation by microbial products. Tollip recruits IRAK1 to the IL1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity. It oligomerizes and binds to TLR2 and the TLR4-MD2 complex via its C terminus. It exists as a complex with IRAK1 in unstimulated cells. Upon IL1 signaling, Tollip binds to the activated IL1 receptor complex containing IL-1RI, IL-1RacP and the adapter protein MyD88, where it interacts with the TIR domain of IL-1RacP. MyD88 then trigg |
| Immunogen | n/a |
| Other Names | [Toll-interacting protein; TOLLIP] |
| Gene, Accession # | [TOLLIP], Gene ID: 54472, NCBI: NP_061882.2, UniProt: Q9H0E2 |
| Catalog # | MBS9202237 |
| Price | $165, $370 |
| Order / More Info | TOLLIP (C-term), 221-250 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhang, G., et al., J. Biol. Chem. 277(9):7059-7065 (2002). Bulut, Y., et al., J. Immunol. 167(2):987-994 (2001). Burns, K., et al., Nat. Cell Biol. 2(6):346-351 (2000). Volpe, F., et al., FEBS Lett. 419(1):41-44 (1997). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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