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Antigenic Specificity | TNFAIP8 (N-term), 50-78 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TNFAIP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human TNFAIP8. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. |
Immunogen | n/a |
Other Names | [Tumor necrosis factor alpha-induced protein 8; TNF alpha-induced protein 8; Head and neck tumor and metastasis-related protein; MDC-313; NF-kappa-B-inducible DED-containing protein; NDED; SCC-S2; TNF-induced protein GG2-1; TNFAIP8] |
Gene, Accession # | [TNFAIP8], Gene ID: 25816, NCBI: NP_001071122.1, UniProt: O95379 |
Catalog # | MBS9212448 |
Price | $165, $370 |
Order / More Info | TNFAIP8 (N-term), 50-78 Antibody from MYBIOSOURCE INC. |
Product Specific References | Dong, Q.Z., et al. Cancer Sci. 101(6):1562-1569(2010) Zhang, L.J., et al. J. Biol. Chem. 284(10):6156-6168(2009) Lamesch, P., et al. Genomics 89(3):307-315(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Kumar, D., et al. Oncogene 23(2):612-616(2004) |