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Antigenic Specificity | IL1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human IL1B (NP 000567.1). |
Other Names | [IL1B; IL-1; IL1-BETA; IL1F2; IL1beta], [IL1B; IL1B; IL-1; IL1F2; IL1-BETA; IL1F2; IL-1 beta] |
Gene, Accession # | [IL1B], Gene ID: 3553, NCBI: P01584.2, UniProt: P01584 |
Catalog # | MBS127158 |
Price | $200, $275, $430 |
Order / More Info | IL1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |